With McF's stuff I do both-
I started with Spawn S-1 and thought it would be a fun thing to collect a companies entire product run. Truthfully, I never thought it would last so long! It's fairly easy to do because I get all my first (moc) sets from my local comic shop-first full set outta the box is mine-then I hunt for a set to open, usually just the Spawn series with a few others thrown in.
I don't get any of the sports stuff.
So with McF's stuff it's MOC first with doubles of some to open.
98% of all the other stuff is open unless it's really rare or really old.
Most of my Disney stuff is moc/mib, though just because it looks better (to me) that way.
There's also a bunch of stuff-mostly Moore's stuff & Full Moon stuff-that's still carded for no particular reason...........
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